Best Hair Serum for Hair Growth

LipiSilk Serum for Intensive Hair Treatment

The LipiSilk hair serum coats and penetrates hair cuticles to repair hair damage and reduce breakage. This helps in slowing down hair loss.

The LipiSilk Hair Serum targets damaged, chemically-treated split ends of hair. The 3 main ingredients include linoleic acid, vitamin E and sea buckthorn oil.

Linoleic acid

Firstly, linoleic acid, or Omega-6, is an essential fatty acid that plays a significant role in hair shaft deep repair. It stimulates hair growth, maintains healthy scalp conditions and reduces hair loss. In a study conducted, linoleic acid was shown to be the most potent known inhibitors of type 1 and 2 forms of 5-alpha reductase (5-AR). 5-AR is the enzyme that converts testosterone into dihydrotestosterone (DHT), which results in greater hair loss. Furthermore, linoleic acid is also highly effective in decreasing the levels of DHT, when applied topically. Hence, linoleic acid is able to reduce hair loss while also contributing to the overall structure of the hair follicle that helps maintain the strength of the hair. 

Bioactive Antioxidant

Secondly, Vitamin E acts as a bioactive antioxidant, assisting with maintaining hair growth. Its natural antioxidant properties could help reduce the amount of oxidative stress and free radicals that cause the hair follicle cells in a person’s scalp to break down. Therefore, Vitamin E can help prevent the breaking down of existing hair follicles. Furthermore, Vitamin E creates a healthy scalp environment as it stimulates the capillaries, which increases the blood flow to the scalp, encouraging hair growth.

Sea Buckthorn Oil 

Lastly, sea buckthorn oil is the purified seed oil of the sea buckthorn plant, Hippophae rhanoides. It contains the strongest antioxidant profile of all superfruits as it includes superoxide dismutase, the super antioxidant, as well as flavonoids, polyphenols, and over 190 phytonutrients. Additionally, sea buckthorn oil helps to protect cells from oxidative damage, aids in collagen production and promotes hair strength and elasticity.

Furthermore, sea buckthorn oil also contains complex lipids such as lecithin, which has skin renewing and moisturizing properties, and helps to remove excess oil from hair. Due to its high content of unsaturated fatty acids, it supports regeneration of damaged hair and restores elasticity, ensuring smoothness. It also strengthens the structure of the hair, making it an effective remedy against hair loss.

LipiGro Serum Scalp Essence 

The LipiGro serum works to inhibit 5a-reductase and promote hair growth. It is suitable and recommended for all types of hair loss including male and female pattern hair loss as well as androgenetic alopecia.

The LipiGro Hair Serum helps in hair regrowth and contains 5a-reductase inhibitor, a growth stimulant, and the purified seed oil of ethanolic extract of safflower.

Learn more about hair loss in our podcast, Dermatologist Talks: Science of Beauty Ep 36.

5a-reductase inhibitor 

As mentioned above, 5-alpha reductase is the enzyme that converts testosterone into dihydrotestosterone (DHT), which results in greater hair loss. By directly including a 5a-reductase inhibitor as an ingredient in the hair serum, it is able to reverse hormonal hair loss by preventing the conversion of testosterone into DHT. 

Purified seed oil of ethanolic extract of safflower

Also known as Carthamus tinctorius L, “The use of safflower oil has been incorporated in hair serums so as to stimulate hair follicles and heal the hair shaft. It helps in the prevention and treatment of hair loss,” accredited dermatologist Dr. Teo Wan Lin. 

In a 2011 study published in the Journal of Ethnopharmacology by Naphatsorn Kumar, safflower extract was found to be the most potent inhibitor of the 5-alpha reductase enzyme as well as the strongest hair growth promoter among 17 Thai plants traditionally used for hair treatment. It was also found that safflower oil encourages hair growth by promoting the proliferation of both dermal papilla cells and HaCaT and by stimulating hair growth-promoting genes. At the same time, it suppresses the expression of the hair loss-related gene. As a result, safflower extract significantly increased the length of cultured hair follicles and stimulated the growth of hair.

LipiShine Serum

The LipiShine serum coats and penetrates hair cuticles to repair UV/chemical induced damage as well as to increase shine and smoothness.

The LipiShine Hair Serum contains 3 main ingredients, namely linoleic acid and the purified seed oil of ethanolic extract of safflower as well as oleic acid, dermatologist-formulated to promote hair shine. 

Oleic acid 

Oleic acid, also called Omega-9, is an unsaturated fatty acid that helps to control water loss in our hair, making out hair softer and smoother. It has been known for a long time to be a penetration enhancer, reported to enhance topical absorption into the scalp and skin. It is also an emollient, acting as an anti- humectant or sealer. Additionally, it’s also a lubricant that provides increased slip between hair strands, preventing tangling. It also reduces tangling in general by smoothing and flattening the cuticle surface, adding shine and gloss to the hair. 

Carthamus Tinctorius (Safflower) Oil 

Secondly, safflower oil comes from the seeds of the safflower plant, and is a rich source of fatty acids. Research has also shown that it is a potent hair growth promoter. 5α-reductase is the enzyme that converts testosterone into the androgen DHT, resulting in hair loss. When tested for 5α-reductase inhibition using enzymes from rat livers and hair growth promoting activity in mice, safflower extract was found to be the most potent inhibitor of the enzyme and the strongest hair growth promoter among 17 Thai plants traditionally used for hair treatment.

It was found that safflower oil encourages hair growth by promoting the proliferation of both dermal papilla cells and HaCaT. Also, by stimulating hair growth-promoting genes such as the vascular endothelial growth factor and keratinocyte growth factor. At the same time, it suppresses the expression of the hair loss-related gene, the transforming growth factor‐β1. As a result, the treatment of hair using safflower extract significantly increased the length of cultured hair follicles and stimulated the growth of hair.

Additionally, several case reports have described clinical improvement in scalp dermatitis, alopecia, and hair depigmentation with topical application of safflower oil (which is rich in omega-6 polyunsaturated fatty acid, the linoleic-acid-precursor of AA). 

Linoleic acid

Linoleic acid is the polyunsaturated fatty acid that comes from the Omega-6 fatty acid group. Considered an essential fat, it is found in plant oils. Linoleic acid stimulates hair growth, and helps us to maintain a healthy scalp microbiome. It also helps our hair to lock in and retain water, ensuring each strand stays optimally hydrated. To illustrate, one study showed that scalp dermatitis, alopecia, and depigmentation of hair were reversed after continued topical application of safflower oil, which contains 60-70% linoleic acid. 

LipiSeries Hair Serum Bundle

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